Yury Popov

Yury Popov

Company: Harvard Medical School

Job title: Division of Gastroenterology, Hepatology & Nutrition


Closing the Gap Between Pre-Clinical Efficacy Testing & Human Clinical Trials Practices in Fibrotic NASH: The Key to Successful Translation 12:00 pm

• Understanding why in diseases associated with progressive fibrosis such as NASH, there is a fundamental methodological discordance between efficacy testing in animal models of liver fibrosis and clinical trials in humans. These include treating too early and mild disease in animals and relying on “surrogate” endpoints that are not reflecting the therapeutic goal in…Read more

day: Day 1 Stream 2 AM

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