Jay Chuang

Company: Gilead

Job title: Senior Scientist

Bio:

Jay Chuang is a biomarker scientist with extensive knowledge in the design and execution of biomarker activities in pre-clinical and clinical stage NASH programs. He has a broad knowledge base in the disciplines of metabolism, endocrinology, inflammation, neuroscience, and fibrosis. Past research projects have involved revealing the novel metabolic roles of orphan nuclear receptors (ONRs), GPCRs, and lysosomal transporters/enzymes in key tissues including pancreatic beta-cells, liver, and central nervous system (CNS).

Jay’s current work focuses on the discovery and validation of novel NASH non-invasive biomarkers (NNIBs) for diagnosis and monitoring of fibrosis stage and NAS components (steatosis, lobular inflammation, and hepatic ballooning) using samples from NASH clinical trials.