Inflammasomes & Downstream Signalling as Novel Targets for Fibrotic NASH

Time: 11:30 am
day: Day 1 Stream 1 AM


• Describing experimental and human evidence for the role of inflammasome pathways in fibrotic NASH development
• Reviewing mechanisms of NLRP3 driven hepatic stellate cells activation
• Dissecting novel downstream signals including IL-18 and caspase 1 dependent pyroptotic cell death in liver fibrosis