Discovering PNPLA3 Antisense Oligonucleotides: Novel Precision Medicine Approach to Treat NASH

Time: 11:00 am
day: Day 2 Stream 1 AM

Details:

• Exploring genetic targets in NASH and the concept of precision medicine for the treatment of the disease
• Analyzing the biology of PNPLA3 and mechanistic insights on how a point mutation in the gene associates with NASH
• Understanding silencing hepatic PNPLA3 by using a liver targeted GalNAc-conjugated antisense oligonucleotide in NASH

Speakers: