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Mechanistic Science Deep Dives

Workshop A - 9 AM

Epigenetic Mechanisms Governing Liver Fibrogenesis Delineating & Utilizing the Complexities of Fibrosis Pathology

Speakers:

Jelena Mann, Professor of Epigenetics, Newcastle University

 

Mark Feitelson, Chief Scientific Officer, SFA Therapeutics

Workshop B - 1 PM

Inflammation & Inflammasome Modulation to Treat NASH & Liver Fibrosis

Speakers:

Ariel Feldstein (Keynote Speaker) Professor & Chief, Pediatric Gastroenterology UC San Diego, Founder Jecure Therapeutics

Davide Povoro Senior Research Scientist Department of Biochemistry & Molecular Biology Mayo Clinic 

New to NASH

 

Workshop C - 9 AM

9.00 Assessing the Translational Relevance & Robustness of Preclinical Modalities to More Confidently Progress NASH Candidates into the Clinic

Speakers:

Bryan Fuchs, Therapeutic Area Head, GI & Liver Disease Ferring Pharmaceuticals

 

Chandra Saravanan, Senior Veterinary Pathologist Novartis Institutes for BioMedical Research (NIBR)

Workshop D - 1 PM

Getting to Grips with the Non-Invasive Evaluation of NAFLD & NASH: A Crash Course for Imaging to Quantify Fibrosis in NASH

Speakers:

Peter Caravan, Co-Director,Institute for Innovation in Imaging, Massachusetts General Hospital

Hannah Drescher, Postdoctoral Researcher, Massachusetts General Hospital

Further than NASH

 

Workshop E - 9 AM

Understanding Hepatocellular Carcinoma as an Extension of NASH Cirrhosis

Speakers:

Bin Gao (Keynote Speaker), Chief, Laboratory of Liver Diseases, NIAAA, NIH

Paul Monga (Keynote Speaker) Director Pittsburgh Liver Research Center, University of Pittsburgh, School of Medicine

Yury Popov, Assistant Professor of Medicine, Harvard Medical School

Clinical Workshops

 

Workshop G - 9 AM

Drug Safety in NASH: Drugging an Impaired Liver

Speakers:

Ajit Dash, Safety Science Associate Medical Director, Genentech

Melissa Palmer, Independent Consultant (Formerly) Head of Liver Disease Development, Takeda

Workshop H - 1 PM

Pediatric NAFLD/NASH Drug Development: Regulatory Guidelines, Challenges & Opportunities

Speakers:

Johannes Taminiau (Keynote Speaker) Pediatric Committee (PDCO) European Medicines Agency (EMA), Pediatric Gastroenterologist University Hospital Antwerp/Paola Children’s Hospital (Belgium)

Manu Chakravarty, Chief Medical Officer & Senior Vice President, Axcella Health

Naim Alkhouri, Director of the Metabolic Center, The Texas Liver Institute