Tuesday December 15, 2020

Mechanistic Science Deep Dives

Workshop A - 10.30 AM

Epigenetic Mechanisms Governing Liver Fibrogenesis Delineating & Utilizing the Complexities of Fibrosis Pathology

Speaker:

Jelena Mann, Professor of Epigenetics, Newcastle University

Workshop B - 1.30 PM

Inflammation & Inflammasome Modulation to Treat NASH & Liver Fibrosis

Speakers:

Ariel Feldstein (Keynote Speaker) Professor & Chief, Pediatric Gastroenterology UC San Diego, Founder Jecure Therapeutics

Davide Povero Senior Research Scientist Department of Biochemistry & Molecular Biology Mayo Clinic 

Gyongyi Szabo Vice Chair for Research, Department of Medicine, University of Massachusetts Medical School 

Models & Imaging:
Where to Start?

Workshop C - 10.30 AM

Getting to Grips with the Non-Invasive Evaluation of NAFLD & NASH: A Crash Course for Imaging to Quantify Fibrosis in NASH

Speakers:

Peter Caravan, Co-Director, Institute for Innovation in Imaging, Massachusetts General Hospital

Hannah Drescher, Postdoctoral Researcher, Massachusetts General Hospital

 

Workshop D - 1.30 PM

Assessing the Translational Relevance & Robustness of Preclinical Modalities to More Confidently Progress NASH Candidates into the Clinic

Speakers:

Bryan Fuchs, Therapeutic Area Head, GI & Liver Disease Ferring Pharmaceuticals

Chandra Saravanan, Senior Veterinary Pathologist Novartis Institutes for BioMedical Research (NIBR)

 

Considerations
Beyond Efficacy

Workshop E - 10.30 AM

Understanding Hepatocellular Carcinoma as an Extension of NASH Cirrhosis

Speakers:

Bin Gao (Keynote Speaker), Chief, Laboratory of Liver Diseases, NIAAA, NIH

Paul Monga (Keynote Speaker) Director Pittsburgh Liver Research Center, University of Pittsburgh, School of Medicine

Yury Popov, Assistant Professor of Medicine, Harvard Medical School

Workshop F - 1.30 AM

Drug Safety in NASH: Drugging an Impaired Liver

Speakers:

Ajit Dash, Safety Science Associate Medical Director, Genentech

Melissa Palmer, Independent Consultant (Formerly) Head of Liver Disease Development, Takeda