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May 4-6, 2020 | Boston, MA

 

Lead Partner

ICON plc is a global provider of clinical development solutions and services to the pharmaceutical, biotechnology and medical device industries. The company specialises in the strategic development, management and analysis of programs that support clinical development. With headquarters in Dublin, Ireland, ICON currently, operates from 84 locations in 38 countries and has approximately 12,300 employees.

www.iconplc.com


 

Senior Partner

PPD is a leading global contract research organization providing comprehensive, integrated drug development, laboratory  and life cycle management services. Our clients and partners include pharmaceutical, biotechnology, medical device, academic and government organizations. With offices in 47 countries and approximately 20,000 professionals worldwide, PPD applies innovative technologies, therapeutic expertise and a firm commitment to quality to help clients and partners bend the cost and time curve of drug development and optimize value in delivering life-changing therapies to improve health.

www.ppd.com


 

Senior Partner

ProSciento is a leading specialty clinical research organization (CRO) exclusively focused on NASH, diabetes, obesity and related metabolic diseases. ProSciento works with biopharma companies worldwide to support their outsourced clinical research needs with comprehensive and customized services for multinational, early development clinical trial programs. Founded in 2003, ProSciento has conducted more than 280 clinical projects for diabetes, NASH and obesity and supported the development of many approved metabolic drugs and devices on the market globally.

www.prosciento.com


 

Senior Partner

Siemens Healthineers enables healthcare providers worldwide to increase value by empowering them on their journey towards expanding precision medicine, transforming care delivery, improving patient experience and digitalizing healthcare. A leader in medical technology, Siemens Healthineers is constantly innovating its portfolio of products and services in its core areas of diagnostic and therapeutic imaging and in laboratory diagnostics and molecular medicine. Siemens Healthineers is also developing its digital health and enterprise services.

www.siemens-healthineers.com


 

Program Partner

Barc Lab is a central laboratory with over 35 years of experience in clinical trials. Barc Lab comprises a global network of labs in the Americas, Europe, Africa, and the Asia Pacific region and acts as a genuine partner providing scientific expertise and a strong portfolio in the NASH field. OWL is a leading biotech company in the field of metabolomics developing and commercializing pioneering diagnostics products for high prevalence diseases, including NASH.

www.barclab.com


 

Program Partner

HepQuant-SHUNT, -STAT, and -FLOW are sensitive, reproducible, accurate, and minimally-invasive tests of global liver function and physiology. They target not only the liver but also the portal circulation and generate a Disease Severity Index (DSI), which ranges from 0 (healthy) to 50 (severe liver disease). DSI may be used for measuring severity of liver disease, tracking disease progression, and monitoring treatment effects. HepQuant’s services include study design, training, consultation, Test Kits, and Laboratory Analyses.

www.hepquant.com


 


Program Partner

Kunming Biomed International (KBI) is a world leading CRO providing preclinical research services that specialized in nonhuman primates (NHPs).  Led by an experienced international team, KBI has collaborated with over 18 large pharmas using translational NHP models for pharmacological efficacy and safety evaluations, including NASH/fibrosis, diabetes and diabetic complications (nephropathy, retinopathy), and cardiovascular diseases (dyslipidemia, heart failure), etc.  KBI has state-of-the-art AAALAC accredited animal research facilities, and extensive colonies (>6000) of healthy and diseased models.

www.kbimed.com


 


Program Partner

Syneos Health™ is the only fully integrated biopharmaceutical solutions organization. Our company, including a Contract Research Organization (CRO) and Contract Commercial Organization (CCO), is purpose-built to accelerate customer performance. Created through the merger of INC Research and inVentiv Health, we bring together more than 23,000 clinical and commercial minds with the ability to support customers in more than 110 countries. To learn more about how we are shortening the distance from lab to life®

www.syneoshealth.com


 


Program Partner

WuXi NextCODE is a life sciences company building the global standard platform for genomic data. With offices in Shanghai; Dublin; Kendall Square in Cambridge, Massachusetts; and Reykjavik, Iceland, we serve the leading population genomics, precision medicine, diagnostics, and wellness enterprises using the genome to improve health around the world. Our capabilities span cohort sourcing, study design, sequencing, scalable analytics including secondary and tertiary analysis, data storage, and AI and deep learning.

www.wuxinextcode.com


 

Spotlight Partner

Continuum Clinical is a global clinical trial enrollment company. With over twenty-five years of experience, Continuum Clinical specializes in providing sponsors and CROs with patient recruitment and retention planning, study and site support, patient recruitment campaigns, patient advocacy and diversity & inclusion services, retention solutions, and reporting and analytics.

www.continuumclinical.com


 

Spotlight Partner

CrownBio’s metabolic disease portfolio is a unique continuum of translational platforms that enable our clients to take strategic go/no-go decisions as they progress their therapeutic candidates through various stages of drug development. Our clients engage with these translational platforms, which include rodent and non-human primates, (NHP) to model human liver disease pathologies and use them to predict human efficacy and safety of therapeutic candidates.

www.crownbio.com


 

Spotlight Partner

Organovo develops dynamic, multi-cellular, and fully-human tissues that closely model native architecture and biology.  With the NovoGen Brioprinter® Platform, the Company designs tissues for use in applications spanning pre-clinical safety testing, disease modeling, and regenerative medicine. Tissues are commercially available through its NovoView™ Service Offering and through strategic partnerships. Organovo’s bioprinted tissues enable mechanistic insights into phenotypes that progress over time and that require multiple cell types in a specific spatial organization, reflecting the true complexity of human biology.

www.organovo.com


 

Spotlight Partner

Woodland Biosciences is a science-based preclinical CRO focused on metabolic liver diseases and deadly cancers.  Our science base allows us to go beyond just running your experiment to participating in the optimal model development and analyses based on our experience and know-how. We are small enough to be flexible and responsive to your experimental design and needs. We run metabolic-driven NASH, chemically-induced liver fibrosis and xenografts in liver, pancreas and brain cancers among others.

www.woodlandbiosciences.com

 


 

Spotlight Partner

ZS is a professional services firm that works side by side with companies to help develop and deliver products that drive customer value and company results. We leverage our deep industry expertise, leading-edge analytics, technology and strategy to create solutions that work in the real world. With more than 35 years of experience and 6,000-plus ZSers in 24 offices worldwide, we are passionately committed to helping companies and their customers thrive.

www.zs.com


 

Diagnostics Partner

Perspectum Diagnostics provides digital health solutions for liver and metabolic diseaseLiverMultiScan, uses multiparametric MRI to provide quantitative analysis of liver tissue, measuring fat and correlates of iron and fibroinflammatory disease. There is a burgeoning interest in using LiverMultiScan in clinical practice to improve the patient pathway and experience, as research has shown that LiverMultiScan correlates with biopsy and clinical outcomes. As well as, MRCP+, which allows 3D visualisation and quantitative mapping of the pancreatobiliary system by enhancing conventional MRCP images.

www.perspectum.com


Hosting Partner

High Point Clinical Trials Center has provided comprehensive (Phase I-III) clinical site services since 2008.  Our 42,000 ftfacility consists of three unique units for the execution of outpatient and inpatient clinical studies.  In addition to Healthy Normal studies, HPCTC focuses on specialty populations such as Metabolic Diseases, NASH, Renal Impairment, Respiratory, CNS, Cardiovascular and Nicotine.

www.highpointctc.com


 

Hosting Partner

Summit Clinical Research is a specialized NASH clinical trial site network. Summit has established a group of NASH expert sites with a proven history of consistent enrollment of highly qualified patients into active trials with the capacity to utilize the most advanced ultrasound and MR based technology. Through key opinion leader and expert guidance on study design and recruitment strategies, Summit provides comprehensive site recruitment and engagement strategy to efficiently and cost-effectively achieve the target patient enrollment goals within optimal timelines.

www.SummitClinicalResearch.com


Exhibition Partner

Bioclinica is a global life sciences solution provider that utilizes science and technology to bring clarity to clinical trials. Bioclinica’s cloud-based offerings include medical imaging, cardiac safety, clinical adjudication, randomization and trial supply management, clinical trial management, electronic data capture and eSource, site and patient payments, pharmacovigilance, and a global network of investigative sites.

www.bioclinica.com


Exhibition Partner

Visit Diapharma to discuss K18 assays as prescreening tools and secondary endpoints in NASH clinical trials. Learn about our panels of mechanistic biomarkers that provide insight into the biological processes occurring during liver injury. Keratin/Keratin 18 (CK18/K18) is an important biomarker of hepatocyte cell death. Explore M30/M65 ELISAs for measuring hepatocyte apoptosis/necrosis non‐invasively. Diapharma offers additional assays for liver injury, including HA, α‐GST, and Collagen IV. For research use only in the U.S. and Canada.

www.diapharma.com


 

Exhibition Partner

Jubilant Chemsys Limited and Jubilant Biosys Limited; sister concerns of Jubilant LifeSciences ($1,171MM Sales Corporation) providing innovative drug discovery services through its research centre’s in India. Our services:

  • TI/ TV to LO/ Preclinical candidate, for multiple therapeutic areas viz; Oncology, Metabolic Disorders, CNS, Pain, Inflammation, Fibrosis and Respiratory diseases
  • Functional services: computational chemistry/ molecular modelling, medicinal chemistry, synthetic chemistry, scale-up (Non-GMP & GMP), structural biology, ADME-PK, in-vitro and in-vivo biology and IND enabling GLP toxicology

www.jubilantbiosys.com


 

Exhibition Partner

OracleBio is a leading digital pathology service provider with in-depth expertise in supporting NASH/NAFLD & Fibrosis research. Utilising Visiopharm Oncotopix and Indica Labs Halo image analysis software, we provide detailed quantification of cells and biomarkers in liver tissue including immune/inflammatory cell count, collagen levels, vacuole content and fibrotic lesion area in stained histology / IHC tissue slides. We deliver cell-by-cell data for improved study interpretation and decision making in preclinical and clinical R&D.

www.oraclebio.com


 

Exhibition Partner

 

Over its 30 year history, Pacific Biomarkers has maintained a “fit-for-purpose” assay development and validation philosophy. We have participated in over 45 studies (Phase I-III) in the last four years alone with a NASH or related indication (primary biliary cirrhosis, chronic hepatitis B, alcoholic hepatitis, hepatobiliary disorders). We have created a menu of tests that complement the research in chronic liver disease; in particular NAFLD/NASH to capture specific liver pathology.

www.pacbio.com

 


Exhibition Partner

Prometheus is committed to improving lives through the development and commercialization of novel pharmaceutical and diagnostic products that enable physicians to provide greater individualized patient care. We are primarily focused on the detection, diagnosis and treatment of disorders within the fields of gastroenterology and oncology.

www.prometheuslabs.com


 

Partner

Physiogenex is a preclinical CRO providing original and benchmarked animal models of obesity/type 2 diabetes and related co-morbidities: NASH, dyslipidemia, inflammation, diabetic nephropathy and cardiovascular complications. For >15 years, we have been evaluating the efficacy of our clients' drugs using gold-standard and radio-tracer based experiments in our validated preclinical models. Our customers benefit from our experience in drug development and expertise in metabolic diseases, as demonstrated by our numerous co-publications with our industrial partners.

www.physiogenex.com


 

Partner

AES is the world’s largest site network, with 200 sites and 1,500+ employees. We provide customers with access to more than 100 million patients in key clinical development markets including the United States, Europe, Africa and Asia. Synexus has unmatched capacity to find the right patient for the right trial at the right time. Our global scale and world-class site network delivers unparalleled capability, data-driven site selection and activation, proven patient engagement and retention expertise.

globalaes.com


Partner

The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institute combining innovation, reliability, and commitment to customer service to provide the most clinically relevant mouse models and precision in vivo services. With an extensive and ever-expanding portfolio of mouse models and services such as target validation and drug efficacy studies, JAX is committed to providing researchers with the most advanced tools to support their research and enable efficacious drug design.

www.jax.org